• Product NameDimethylenastron
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityDimethylenastron is an Eg5 inhibitor, which arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.
• Target NameKinesin inhibitor
• CAS No. 863774-58-7
• Calculated MW 302.39
• Formulation C16H18N2O2S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CC1(CC2=C(C(NC(=S)N2)C3=CC(=CC=C3)O)C(=O)C1)C
  Pathways:Cytoskeletal Signaling
  Receptor:Eg5
  Boling pt:
  Melting pt:
  Solubility:DMSO: 31 mg/mL
  Appearance:Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Aljaberi AM, et al. Cell Cycle. 2015;14(11):1738-47.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting