• Product NameSC66
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivitySC66 is a novel AKT inhibitor, IC50 values of approximately 0.75 μg/ml at 72 hours in HepG2, HA22T/VGH and PLC/PRF/5 cells.
• Target NameAkt inhibitor
• CAS No. 871361-88-5
• Calculated MW 276.33
• Formulation C18H16N2O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C1C/C(=C\C2=CC=NC=C2)/C(=O)/C(=C/C3=CC=NC=C3)/C1
  Pathways:Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
  Receptor:Akt
  Boling pt:
  Melting pt:
  Solubility:DMSO: 34 mg/mL
  Appearance:Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Cusimano A, et al. Oncotarget. 2015 Jan 30;6(3):1707-22.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting