• Product NameMirin
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityMirin is a potent Mre11CRad50CNbs1 (MRN) complex inhibitor, and inhibits Mre11-associated exonuclease activity.?
• Target NameATM/ATR inhibitor
• CAS No. 1198097-97-0
• Calculated MW 220.25
• Formulation C10H8N2O2S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C1=CC(=CC=C1/C=C\2/C(=O)N=C(S2)N)O
  Pathways:DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
  Receptor:MRN
  Boling pt:
  Melting pt:
  Solubility:DMSO: 44 mg/mL (199.77 mM)
  Appearance:Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Edwards TG, et al. PLoS One. 2013 Oct 2;8(10):e75406.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting