• Product NameWnt agonist 1 (BML-284)
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityWnt agonist 1 is a cell permeable?Wnt?signaling pathway activator, which induces β-catenin- and TCF-dependent transcriptional activity with EC50 of 0.7 μM.
• Target NameWnt/beta-catenin inhibitor
• CAS No. 853220-52-7
• Calculated MW 386.83
• Formulation C19H18N4O3HCl
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:COC1=CC=CC(=C1)C2=CC(=NC(=N2)N)NCC3=CC4=C(C=C3)OCO4
  Pathways:Cytoskeletal Signaling; Stem Cells
  Receptor:Wnt
  Boling pt:
  Melting pt:
  Solubility:DMSO: 77 mg/mL (199.05 mM)
  Appearance:Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Liu J, et al. Angew Chem Int Ed Engl. 2005 Mar 18;44(13):1987-90.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting