• Product NamePD1-PDL1 inhibitor 2
• Brief DescriptionInhibitors
• Purification98.54%
• Biological ActivityPD1-PDL1 inhibitor 2 is a inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction, extracted from patent WO/2015034820 A1, compound example 202.
• Target NamePD-1/PD-L1 inhibitor
• CAS No. 1675203-84-5
• Calculated MW 419.52
• Formulation C25H29N3O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CC1=C(COC2=CC=C(CNCCNC(C)=O)C(OC)=N2)C=CC=C1C3=CC=CC=C3
  Pathways:Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
  Receptor:PD-1/PD-L1
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:WhitePowder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Louis S. Chupak, et al. Compounds useful as immunomodulators

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting