• Product NameHUHS015
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityHUHS015 is a potent PCA-1/ALKBH3 inhibitor. The bioavailability of HUHS015 was 7.2% in rats after oral administration. HUHS015 significantly suppressed the growth of DU145 cells, which are human hormone-independent prostate Y cells, in a mouse xenograft model without untoward effects.
• Target NameOthers inhibitor
• CAS No. 1453097-13-6
• Calculated MW 318.14
• Formulation C19H18N4O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:OC1=C(CC2=CC=CC=C2)C(C)=NN1C3=NC4=CC(C)=CC=C4N3
  Pathways:Others
  Receptor:PCA-1/ALKBH3 inhibitor
  Boling pt:
  Melting pt:
  Solubility:DMSO: 34 mg/mL
  Appearance:Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Nakao S, et al. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1071-4.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting