• Product NameIDE1
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityIDE1 is a small molecule capable of inducing definitive endoderm from embryonic stem cells. It has been shown to induce the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mouse embryonic stems cells (EC50?= 125.5 nM?in vitro) by activating the TGF-β signaling pathway.?IDE1-derived endodermal cells injected into E8.75 mouse embryos?ex vivo?have been shown to incorporate into the developing gut tube, contributing to its formation.
• Target NameOthers
• CAS No. 1160927-48-9
• Calculated MW 306.3
• Formulation C15H18N2O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C1=CC=C(C(=C1)/C=N/NC(=O)CCCCCC(=O)O)C(=O)O
  Pathways:Others
  Receptor:Others
  Boling pt:
  Melting pt:
  Solubility:DMSO: 30 mg/mL
  Appearance:Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Hoveizi E, et al. J Biomed Mater Res A. 2014 Nov;102(11):4027-36.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting