• Product NameAZ-33
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityAZ-33 is an LDHA inhibitor. Binding affinity to 6-His-tagged human LDHA (2 to 322 amino acid residue) expressed in Escherichia coli BL21 (DE3) cells by SPR analysis with active value of 0.093μM
• Target NameDehydrogenase inhibitor
• CAS No. 1370290-34-8
• Calculated MW 497.56
• Formulation C25H27N3O6S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:OC(C(C(O)=O)CC1=CC=C(CCCC(NCCC(NC2=CC(SC(C)=N3)=C3C=C2)=O)=O)C=C1)=O
  Pathways:Metabolism
  Receptor:LDHA
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Ward RA, et al.J Med Chem. 2012 Apr 12;55(7):3285-306.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting