• Product NameAPD597
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityAPD597 is a GPR119 agonist intended for the treatment of type 2 diabetes, with EC50 of 46 nM for hGPR119.
• Target NameGPR agonist
• CAS No. 897732-93-3
• Calculated MW 479.55
• Formulation C21H29N5O6S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:COC1=C(NC2=C(C)N=C(C=C2)S(C)(=O)=O)N=CN=C1OC1CCN(CC1)C(=O)OC(C)C
  Pathways:Endocrinology/Hormones
  Receptor:GPR119
  Boling pt:
  Melting pt:
  Solubility:DMSO: 19mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Buzard DJ, et al. Bioorg Med Chem Lett. 2014 Sep 1;24(17):4332-5.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting