• Product NameJNJ-42041935
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityJNJ-42041935 is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes.
• Target NameHIF/HIF Prolyl-Hydroxylase inhibitor
• CAS No. 1193383-09-3
• Calculated MW 346.65
• Formulation C12H6ClF3N4O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:OC(=O)C1=CN(N=C1)C1=NC2=CC(OC(F)(F)F)=C(Cl)C=C2N1
  Pathways:Metabolism; Chromatin/Epigenetic
  Receptor:PHD1; PHD2; PHD3
  Boling pt:
  Melting pt:
  Solubility:DMSO: 36mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Barrett TD, et al. Mol Pharmacol. 2011 Jun;79(6):910-20.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting