• Product NameSW044248
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivitySW044248 is a novel noncanonical Top1 inhibitor with a pattern of selective toxicity for NSCLC cells.
• Target NameTopoisomerase inhibitor
• CAS No. 522650-83-5
• Calculated MW 421.52
• Formulation C22H23N5O2S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CCC(SC1=NC2=C(N=N1)C1=CC=CC=C1N2CC)C(=O)NC1=CC=CC=C1OC
  Pathways:DNA Damage/DNA Repair
  Receptor:Topo I
  Boling pt:
  Melting pt:
  Solubility:DMSO: 40mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Zubovych IO, et al. Mol Y Ther. 2016 Jan;15(1):23-36.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting