• Product NameL-778123 hydrochloride
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityL-778123 hydrochloride is an inhibitor of FPTase and GGPTase-I with IC50 of 2 nM and 98 nM in enzyme inhibition determination.
• Target NameTransferase inhibitor
• CAS No. 253863-00-2
• Calculated MW 442.34
• Formulation C22H21Cl2N5O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:Cl.ClC1=CC=CC(=C1)N1CCN(CC2=CN=CN2CC2=CC=C(C=C2)C#N)CC1=O
  Pathways:Metabolism
  Receptor:Farnesyl transferase (FTase)
  Boling pt:
  Melting pt:
  Solubility:DMSO: 25mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Lobell RB, et al. Mol Y Ther. 2002 Jul;1(9):747-58.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting