• Product NameWAY-181187(SAX-187)
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityWAY-181187 possess high affinity binding (2.2 nM) at the human 5-HT6 receptor and profile as full receptor agonists (WAY-181187: EC50=6.6 nM, Emax=93%).
• Target Name5-HT Receptor antagonist
• CAS No. 554403-49-5
• Calculated MW 380.87
• Formulation C15H13ClN4O2S2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:NCCC1=CN(C2=CC=CC=C12)S(=O)(=O)C1=C(Cl)N=C2SC=CN12
  Pathways:GPCR/G Protein; Neuroscience
  Receptor:5-HT6
  Boling pt:
  Melting pt:
  Solubility:DMSO: 11 mM
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Schechter LE, et al. Neuropsychopharmacology. 2008 May;33(6):1323-35.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting