• Product NamePimelic diphenylamide 106
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityPimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I HDAC (HDAC 1, 2, and 3, with IC50 values of 150 nM , 760nM, and 370 nM, respectively), demonstrating no activity against class II HDACs.
• Target NameHDAC inhibitor
• CAS No. 937039-45-7
• Calculated MW 339.43
• Formulation C20H25N3O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CC1=CC=C(NC(=O)CCCCCC(=O)NC2=CC=CC=C2N)C=C1
  Pathways:Chromatin/Epigenetic; DNA Damage/DNA Repair; NF-κb
  Receptor:HDAC
  Boling pt:
  Melting pt:
  Solubility:DMSO: 30mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Chou CJ, et al. J Biol Chem. 2008 Dec 19;283(51):35402-9.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting