• Product NameWDR5-0103
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityWDR5-0103 is a potent and selective WD repeat-containing protein 5 (WDR5) antagonist with Kd of 450 nM.
• Target NameJAK inhibitor
• CAS No. 890190-22-4
• Calculated MW 383.44
• Formulation C21H25N3O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:COC(=O)C1=CC(NC(=O)C2=CC(OC)=CC=C2)=C(C=C1)N1CCN(C)CC1
  Pathways:Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
  Receptor:WDR5
  Boling pt:
  Melting pt:
  Solubility:DMSO: 40mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Senisterra G, et al. Biochem J. 2013 Jan 1;449(1):151-9.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting