• Product NameNS-398
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityCOX-2 inhibitor and anti-inflammatory agent
• Target NameCOX inhibitor
• CAS No. 123653-11-2
• Calculated MW 314.36
• Formulation C13H18N2O5S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CS(=O)(=O)NC1=C(OC2CCCCC2)C=C(C=C1)[N+]([O-])=O
  Pathways:Immunology/Inflammation; Neuroscience
  Receptor:COX-2
  Boling pt:
  Melting pt:
  Solubility:DMSO: > 10 mM
  Appearance:YellowPowder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Kim J, et al. COX-2 inhibitor NS-398 suppresses doxorubicin-induced p53 accumulation through inhibition of ROS-mediated Jnk activation. Mol Carcinog. 2016 Jan 12. doi: 10.1002/mc.22458.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting