- Product NameJNJ-42165279
- Brief DescriptionInhibitors
- Purification99.00%
- Biological ActivityJNJ-42165279 covalently inactivates the FAAH enzyme, but is highly selective with regard to other enzymes, ion channels, transporters, and receptors. JNJ-42165279 exhibits high selectivity against a panel of 50 receptors, enzymes, transporters, and ion-channels at 10 μM, at which concentration it does not produce >50% inhibition of binding to any of the targets. Fortunately, JNJ-42165279 also does not inhibit CYPS (1A2, 2C8, 2C9, 2C19, 2D6, 3A4) or hERG when tested at a 10 μM compound concentration.
- Target NameFAAH inhibitor
- CAS No. 1346528-50-4
- Calculated MW 410.8
- Formulation C18H17ClF2N4O3
- Storage 3 years -20˚C powder;2 years -80˚C in solvent;
