• Product NamePF-CBP1 hydrochloride
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityPF-CBP1 is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP).It inhibits CREBBP and p300 bromodomains with IC50 of 125 and 363 nM respectively.
• Target NameEpigenetic Reader Domain inhibitor
• CAS No. 2070014-93-4
• Calculated MW 525.08
• Formulation C29H37ClN4O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CCCOC(C=C1)=CC=C1CCC2=NC3=CC(C4=C(C)ON=C4C)=CC=C3N2CCN5CCOCC5
  Pathways:Chromatin/Epigenetic
  Receptor:CREBBP; p300/CBP
  Boling pt:
  Melting pt:
  Solubility:DMSO: 100 mg/mL
  Appearance:WhitePowder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Chekler EL, et al. Chem Biol. 2015 Dec 17;22(12):1588-96.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting