• Product NameParitaprevir
• Brief DescriptionInhibitors
• Purification99.66%
• Biological ActivityParitaprevir is a Hepatitis C Virus NS3/4A Protease Inhibitor. The mechanism of action of paritaprevir is as a HCV NS3/4A Protease Inhibitor, and Organic Anion Transporting Polypeptide 1B1 Inhibitor, and Organic Anion Transporting Polypeptide 1B3 Inhibitor, and Breast Y Resistance Protein Inhibitor, and UGT1A1 Inhibitor, and P-Glycoprotein Inhibitor.
• Target NameHCV Protease inhibitor
• CAS No. 1221573-85-8
• Calculated MW 765.89
• Formulation C40H43N7O7S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism/ Immunology
  SMILES:Cc1ncc(nc1)C(=O)N[C@H]5CCCCCC=C[C@@H]8C[C@]8(NC(=O)[C@@H]6C[C@@H](Oc3nc4ccccc4c2ccccc23)CN6C5=O)C(=O)NS(=O)(=O)C7CC7
  Pathways:Microbiology&virology; Proteases/Proteasome
  Receptor:HCV NS3/4A
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Todt D, et al. J Antimicrob Chemother. 2017 Jan 18.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting