• Product NameUNC0638
• Brief DescriptionInhibitors
• Purification98.57%
• Biological ActivityUNC0638 is an inhibitor of?protein lysine methyltransferases G9a(IC50<15 nM) and GLP(IC50=19 nM) with excellent potency and selectivity over a wide range of epigenetic and non-epigenetic targets.
• Target NameHistone Methyltransferase inhibitor
• CAS No. 1255580-76-7
• Calculated MW 509.73
• Formulation C30H47N5O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:COC1=C(OCCCN2CCCC2)C=C2N=C(N=C(NC3CCN(CC3)C(C)C)C2=C1)C1CCCCC1
  Pathways:Chromatin/Epigenetic
  Receptor:G9a; GLP
  Boling pt:
  Melting pt:93-94˚C
  Solubility:DMSO: 34 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Vedadi M, et al.Nat Chem Biol. 2011 Jul 10;7(8):566-74.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting