• Product NamePonesimod
• Brief DescriptionInhibitors
• Purification98.01%
• Biological ActivityPonesimod(ACT-128800) is an orally active, selective sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator.
• Target NameS1P Receptor modulator
• CAS No. 854107-55-4
• Calculated MW 460.97
• Formulation C23H25ClN2O4S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:CCCN=C1N(C(=O)/C(=C/C2=CC(=C(C=C2)OC[C@@H](CO)O)Cl)/S1)C3=CC=CC=C3C
  Pathways:GPCR/G Protein
  Receptor:S1P1
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Piali L, et al. J Pharmacol Exp Ther. 2011 May;337(2):547-56.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting