• Product NameDdr1-In-1
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityDDR1-IN-1 is a potent and selective?discoidin domain receptor 1 (DDR1)?receptor tyrosine kinase inhibitor with?IC50?of 105 nM, about 3-fold selectivity over DDR2.?
• Target NameDopamine Receptor inhibitor
• CAS No. 1449685-96-4
• Calculated MW 552.6
• Formulation C30H31F3N4O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CCN1CCN(CC1)CC2=C(C=C(C=C2)C(=O)NC3=CC(=C(C=C3)C)OC4=CC5=C(C=C4)NC(=O)C5)C(F)(F)F
  Pathways:GPCR/G Protein; Neuroscience
  Receptor:DDR1; DDR2
  Boling pt:
  Melting pt:
  Solubility:DMSO: 100 mg/mL warming (180.96 mM), Ethanol: 4 mg/mL warming (7.23 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Kim HG, et al. ACS Chem Biol. 2013, 8(10), 2145-2150.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting