• Product NameSCR7
• Brief DescriptionInhibitors
• Purification99.85%
• Biological ActivitySCR7 is a molecule that inhibits joining of DSBs in cell-free repair system; inhibits NHEJ(nonhomologous end-joining) in a Ligase IV-dependent manner within cells, and activates the intrinsic apoptotic pathway.
• Target NameDNA/RNA Synthesis inhibitor
• CAS No. 1533426-72-0
• Calculated MW 334.4
• Formulation C18H14N4OS
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C1=CC=C(C=C1)C=NC2=C(NC(=S)NC2=O)/N=C/C3=CC=CC=C3
  Pathways:DNA Damage/DNA Repair
  Receptor:DNALigase IV
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 3 mg/mL warmed (8.97 mM); DMSO: 66 mg/mL (197.37 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Srivastava M, et al. Cell. 2012 Dec 21;151(7):1474-87.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting