• Product NamePF-3274167
• Brief DescriptionInhibitors
• Purification99.67%
• Biological ActivityPF-3274167, also known as PF-03274167 or PF-327,4167, is a potent and selective, high-affinity nonpeptide oxytocin receptor antagonist. Oxytocin receptor, also known as OXTR, is a protein which functions as receptor for the hormone and neurotransmitter oxytocin. Oxytocin receptors are also present in the central nervous system.
• Target NameOX Receptor inhibitor
• CAS No. 900510-03-4
• Calculated MW 419.11
• Formulation C19H19ClFN5O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology/ Endocrine system
  SMILES:COc1ccc(cn1)n2c(nnc2N3CC(C3)Oc4ccc(F)cc4Cl)COC
  Pathways:GPCR/G Protein; Neuroscience
  Receptor:OXTR
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Karpenko IA, et al. J Med Chem. 2015 Mar 12;58(5):2547-52.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting