• Product NamePIK-293
• Brief DescriptionInhibitors
• Purification99.80%
• Biological ActivityPIK-293 is a?PI3K?inhibitor, mostly for?PI3Kδ?with?IC50?of 0.24 μM, 500-, 100- and 50-fold less potent to PI3Kα/β/γ, respectively.
• Target NamePI3K inhibitor
• CAS No. 900185-01-5
• Calculated MW 397.43
• Formulation C22H19N7O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CC1=C2C(=CC=C1)N=C(N(C2=O)C3=CC=CC=C3C)CN4C5=C(C=N4)C(=NC=N5)N
  Pathways:PI3K/Akt/mTOR signaling
  Receptor:p110α; p110β; p110γ; p110δ
  Boling pt:
  Melting pt:
  Solubility:DMSO: 80 mg/mL (201.29 mM)
  Appearance:Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Knight ZA et al. Cell, 2006, 125(4), 733-747.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting