- Product NameCC-223
- Brief DescriptionInhibitors
- Purification99.14%
- Biological ActivityCC-223 is an orally available inhibitor of the mammalian target of rapamycin (mTOR) with potential antitumor activity. mTOR kinase inhibitor CC-223 inhibits the activity of mTOR, which may result in the induction of tumor cell apoptosis and a decrease in tumor cell proliferation. CC-223 is a potent mTOR kinase inhibitor (IC50=16 nM), with >150-fold sensitivity over the related lipid kinase PI3Kα (IC50=4 μM).
- Target Namec-Fms inhibitor; DNA-PK inhibitor; FLT inhibitor; mTOR inhibitor; PI3K inhibitor
- CAS No. 1228013-30-6
- Calculated MW 397.47
- Formulation C21H27N5O3
- Storage 3 years -20˚C powder;2 years -80˚C in solvent;
