• Product NameNuciferine
• Brief DescriptionInhibitors
• Purification97.00%
• Biological ActivityNuciferine is an alkaloid found within the plants Nymphaea caerulea and Nelumbo nucifera. It has a profile of action associated with dopamine receptor blockade. It induces sedation, hypothermia, ptosis, and (in higher doses) catalepsy; it inhibits spontaneous motor activity, conditioned avoidance response, amphetamine toxicity and stereotypy. Nuciferine may also potentiate morphine analgesia.
• Target Name5-HT Receptor antagonist; Dopamine Receptor inhibitor
• CAS No. 475-83-2
• Calculated MW 295.38
• Formulation C19H21NO2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CN1CCC2=CC(=C(C3=C2[C@H]1CC4=CC=CC=C43)OC)OC
  Pathways:GPCR/G Protein; Neuroscience
  Receptor:5-HT2A; 5-HT2B; 5-HT2C; 5-HT7; D5 receptor
  Boling pt:
  Melting pt:
  Solubility:Soluble in Chloroform
  Appearance:White powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Farrell MS, et al. PLoS One. 2016 Mar 10;11(3):e0150602.;

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting