• Product NameMomordin Ic
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityMomordin Ic might represent a potential antiY activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunction involving the MAPK and PI3K-mediated iNOS and HO-1 pathways. Also, Momordin Ic accelerates gastrointestinal transit partially by stimulating synthesis of 5-HT to act through 5-HT(2), which, in turn, increases synthesis of prostaglandins.
• Target NameMAPK; PI3K
• CAS No. 96990-18-0
• Calculated MW 764.93
• Formulation C41H64O13
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)C)C)(C)C)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(=O)O)O)O[C@H]7[C@@H]([C@H]([C@@H](CO7)O)O)O)O
  Pathways:MAPK; PI3K/Akt/mTOR signaling
  Receptor:MAPK; PI3K
  Boling pt:
  Melting pt:
  Solubility:Soluble in Pyridine, Methanol, Ethanol, etc.
  Appearance:Brown powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Wang J, et al. Apoptosis. 2013 Jun;18(6):751-65.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting