• Product NameGRA-Ex-25
• Brief DescriptionInhibitors
• Purification98.20%
• Biological ActivityGRA-Ex-25 is an inhibitor of glucagon receptor, with IC50 of 56 and 55 nM for rat and human glucagon receptors, respectively.
• Target NameGlucagon Receptor inhibitor
• CAS No. 307983-31-9
• Calculated MW 563.61
• Formulation C29H36F3N3O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:C[C@](C1CC[C@H](N(C(NC2C=CC(OC(F)(F)F)=CC=2)=O)CC2C=CC(C(NCCC(O)=O)=O)=CC=2)CC1)(C)C
  Pathways:GPCR/G Protein
  Receptor:human glucagon receptor; rat glucagon receptor
  Boling pt:
  Melting pt:
  Solubility:DMSO: 32 mg/Ml
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Kurukulasuriya R, et al. Bioorg Med Chem Lett. 2004 May 3;14(9):2047-50.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting