• Product NameBAY1217389
• Brief DescriptionInhibitors
• Purification99.54%
• Biological ActivityBAY 1217389 is a potent, and selective inhibitor of the monopolar spindle 1 (MPS1) kinase with an IC50 value less than 10 nM.
• Target NameKinesin inhibitor
• CAS No. 1554458-53-5
• Calculated MW 561.5
• Formulation C27H24F5N5O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CC1=C(C=CC(=C1)C2=CN=C3N2N=C(C=C3NCCC(F)(F)F)OC4=C(C(=C(C=C4)OC)F)F)C(=O)NC5CC5
  Pathways:Cytoskeletal Signaling
  Receptor:Mps1
  Boling pt:
  Melting pt:
  Solubility:DMSO: 28 mg/Ml
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Wengner AM, et al. Mol Cancer Ther. 2016 Apr;15(4):583-92.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting