• Product NameVicriviroc maleate
• Brief DescriptionInhibitors
• Purification97.00%
• Biological ActivityVicriviroc maleate(Sch-417690) is a CCR5 antagonist with IC50 of 0.91 nM in clinical development for the treatment of HIV-1.
• Target NameCCR antagonist
• CAS No. 599179-03-0
• Calculated MW 649.7
• Formulation C32H42F3N5O6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:C[C@H]1CN(CCN1[C@@H](COC)C2=CC=C(C=C2)C(F)(F)F)C3(CCN(CC3)C(=O)C4=C(N=CN=C4C)C)C.C(=C\C(=O)O)\C(=O)O
  Pathways:Immunology/Inflammation; Microbiology&virology
  Receptor:CCR5
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Edward O'Mara, Claudia Kasserra, John Robert Huddlestone,et al. Antimicrob Agents Chemother. 2010; 54(6): 2448-2454.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting