• Product NameS107
• Brief DescriptionInhibitors
• Purification99.63%
• Biological ActivityS107 is a RyR-selective 1,4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels.
• Target NameOthers
• CAS No. 927871-76-9
• Calculated MW 209.31
• Formulation C11H15NOS
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:CN1CCSC2=C(C1)C=C(C=C2)OC
  Pathways:Others
  Receptor:Others
  Boling pt:
  Melting pt:
  Solubility:DMSO: 38 mg/Ml
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Lehnart SE, et al. J Clin Invest. 2008 Jun;118(6):2230-45.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting