• Product NameML348
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityML348 is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM), Exhibits 14-fold selectivity for LYPLA1 over LYPLA2, Also selective over a panel of ~30 other serine hydrolases.
• Target NameOthers inhibitor
• CAS No. 899713-86-1
• Calculated MW 415.79
• Formulation C18H17ClF3N3O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:O=C(NC1=CC(C(F)(F)F)=CC=C1Cl)CN2CCN(C(C3=CC=CO3)=O)CC2
  Pathways:Others
  Receptor:LYPLA1
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Adibekian A, et al. National Center for Biotechnology Information (US); 2010-. 2013 Apr 08 [updated 2014 Jan 13].

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting