• Product NameUK-371804
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityUK-371804 is a potent and selective uPA inhibitor with excellent enzyme potency and selectivity profile, which was selected as a candidate for further preclinical evaluation for the treatment of chronic dermal ulcers.
• Target NameSerine Protease inhibitor
• CAS No. 256477-09-5
• Calculated MW 385.823
• Formulation C14H16ClN5O4S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:CC(C)(NS(=O)(C1=CC2=C(C=C1)C(Cl)=CN=C2/N=C(N)\N)=O)C(O)=O
  Pathways:Proteases/Proteasome
  Receptor:uPA
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Fish PV, Barber CG, Brown DG, Butt R, Collis MG, et al. J Med Chem. 2007 May 17;50(10):2341-51. Epub 2007 Apr 21.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting