• Product NameThiomyristoyl
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityThiomyristoyl is a potent and specific?SIRT2?inhibitor with an?IC50?of 28 nM. It inhibits SIRT1 with an IC50 value of 98 μM and does not inhibit SIRT3 even at 200 μM.
• Target NameSirtuin inhibitor
• CAS No. 1429749-41-6
• Calculated MW 581.85
• Formulation C34H51N3O3S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:O=C(OCC1=CC=CC=C1)N[C@@H](CCCCNC(CCCCCCCCCCCCC)=S)C(NC2=CC=CC=C2)=O
  Pathways:Chromatin/Epigenetic; DNA Damage/DNA Repair
  Receptor:SIRT1; SIRT2
  Boling pt:
  Melting pt:
  Solubility:Chloroform, DMSO
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Jing H, et al. Cancer Cell. 2016 Mar 14;29(3):297-310.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting