• Product NameISCK03
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityISCK03 is a specific SCF/c-Kit inhibitor.
• Target Namec-Kit inhibitor
• CAS No. 945526-43-2
• Calculated MW 355.456
• Formulation C19H21N3O2S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)N3C=CN=C3
  Pathways:Tyrosine Kinase/Adaptors
  Receptor:c-Kit
  Boling pt:
  Melting pt:
  Solubility:DMSO: 38 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Na YJ, et al. [4-t-butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs. Biochem Pharmacol. 2007 Sep 1;74(5):780-6.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting