• Product NameWAY-100635 maleate
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityWAY-100635 maleate is a potent and selective 5-hydroxytryptamine1A antagonist with an IC50 of 0.95 0.12 nM for 5-HT.
• Target Name5-HT Receptor antagonist
• CAS No. 634908-75-1
• Calculated MW 538.645
• Formulation C29H38N4O6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:COC1=CC=CC=C1N2CCN(CC2)CCN(C3=CC=CC=N3)C(=O)C4CCCCC4.C(=C\C(=O)O)\C(=O)O
  Pathways:GPCR/G Protein; Neuroscience
  Receptor:5-HT1A
  Boling pt:
  Melting pt:
  Solubility:DMSO: 34 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Al Hussainy, Rana; Design, Synthesis, Radiolabeling, and in Vitro and in Vivo Evaluation of Bridgehead Iodinated Analogues of N-{2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl}-N-(pyridin-2-yl)cyclohexanecarboxamide (WAY-100635) as Potential SPECT Ligands for the 5-HT1A Receptor. Journal of Medicinal Chemistry (2011), 54(10), 3480-3491.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting