• Product NameARQ-092
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityARQ-092 is an Akt inhibitor extracted from patent US/20150299195A1, compound A.
• Target NameAkt inhibitor
• CAS No. 1313881-70-7
• Calculated MW 432.531
• Formulation C27H24N6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:C1CC(C1)(C2=CC=C(C=C2)N3C4=C(C=CC(=N4)C5=CC=CC=C5)N=C3C6=C(N=CC=C6)N)N
  Pathways:Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
  Receptor:Akt
  Boling pt:
  Melting pt:
  Solubility:DMSO: 40.2 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Craig Bates, et al. Process of preparing 3-(3-(4-(1-aminocyclobutyl)phenyl)-5-phenyl-3h-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amine. US/20150266876/A1

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting