• Product NameBimolane
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityBimolane is a topoisomerase II inhibitor.
• Target NameTopoisomerase inhibitor
• CAS No. 74550-97-3
• Calculated MW 452.512
• Formulation C20H32N6O6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C1COCCN1CN2C(=O)CN(CC2=O)CCN3CC(=O)N(C(=O)C3)CN4CCOCC4
  Pathways:DNA Damage/DNA Repair
  Receptor:Topo II
  Boling pt:
  Melting pt:
  Solubility:DMSO:Soluble
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Vuong MC, Hasegawa LS, Eastmond DA. A comparative study of the cytotoxic and genotoxic effects of ICRF-154 and bimolane, two catalytic inhibitors of topoisomerase II. Mutat Res. 2013 Jan 20;750(1-2):63-71.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting