• Product Name()-trans-ACPD
• Brief DescriptionInhibitors
• Purification98.00%
• Biological Activity(+/-)-1-Aminocyclopentanl-trans-1,3-Dicarboxylic acid is a equimolecular mixture of (1S,3R)- and (1R,3S)-ACPD. (+/-)-1-Aminocyclopentanl-trans-1,3-Dicarboxylic acid is used as a selective agonist of the mGluR (metabotropic glutamate receptor); active at both group I and group II mGlu receptors (EC50 values are 2, 15, 23 and ~800 μM at mGluR2, mGluR1, mGluR5 and mGluR4 respectively).
• Target NameCalcium Channel agonist
• CAS No. 67684-64-4
• Calculated MW 173.168
• Formulation C7H11NO4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C1C[C@@](C[C@H]1C(=O)O)(C(=O)O)N
  Pathways:Membrane transporter/Ion channel
  Receptor:Calcium Channel
  Boling pt:
  Melting pt:
  Solubility: 1eq. NaOH: 50 mM; Water: 5 mM with gentle warming
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Conti P,et al.Synthesis and pharmacology of 3-hydroxy-delta2-isoxazoline-cyclopentane analogues of glutamic acid.Farmaco. 2002 Nov;57(11):889-95.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting