• Product Name1400W dihydrochloride
• Brief DescriptionInhibitors
• Purification99.00%
• Biological Activity1400 W is a highly potent and selective inhibitor of inducible NOS2 (iNOS).
• Target NameNOS inhibitor
• CAS No. 214358-33-5
• Calculated MW 213.709
• Formulation C10H16ClN3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CC(=NCC1=CC(=CC=C1)CN)N.Cl.Cl
  Pathways:Immunology/Inflammation
  Receptor:eNOS; iNOS; nNOS
  Boling pt:
  Melting pt:
  Solubility:DMSO:0.25 mg/ml; DMF :0.25 mg/ml;Ethanol :0.25 mg/ml:Water :100 mM
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Thomsen LL1, Scott JM, Topley P, Knowles RG, Keerie AJ, Frend AJ.Selective inhibition of inducible nitric oxide synthase inhibits tumor growth in vivo: studies with 1400W, a novel inhibitor.Cancer Res. 1997 Aug 1;57(15):3300-4.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting