• Product NameCZ415
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityCZ415 is a potent and highly selective mTOR inhibitor
• Target NamemTOR inhibitor
• CAS No. 1429639-50-8
• Calculated MW 459.56
• Formulation C22H29N5O4S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:O=C(NCC)NC1=CC=C(C2=NC(N3[C@@H](C)COCC3)=C4C(C(C)(C)S(C4)(=O)=O)=N2)C=C1
  Pathways:PI3K/Akt/mTOR signaling
  Receptor:mTOR
  Boling pt:
  Melting pt:
  Solubility:DMSO: 31 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Cansfield AD,et al. CZ415, a Highly Selective mTOR Inhibitor Showing in Vivo Efficacy in a Collagen Induced Arthritis Model. ACS Med Chem Lett. 2016 Jun 10;7(8):768-73.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting