• Product NamePolyphyllin B
• Brief DescriptionInhibitors
• Purification100.00%
• Biological ActivityPolyphyllin B isolated from Rhizoma Paridis, showed pro-apoptosis and immunoregulation with antitumor activity in cultured cells and animal systems.
• Target NameCaspase activator
• CAS No. 50773-42-7
• Calculated MW 1015.2
• Formulation C51H82O20
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C[C@@H]1O[C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@@H]1[C@H]([C@@H](O)[C@@H](O[C@H]1C)O[C@@H]1[C@H](O[C@H]([C@@H]([C@H]1O)O[C@H]1[C@H](O)[C@H](O)[C@@H]([C@@H](C)O1)O)O[C@H]1CC[C@@]2([C@H]3CC[C@@]4([C@@H]([C@@H]3CC=C2C1)C[C@H]1[C@@H]4[C@H](C)[C@]2(CC[C@H](CO2)C)O1)C)C)CO)O
  Pathways:Apoptosis; Proteases/Proteasome
  Receptor:Caspase-2
  Boling pt:
  Melting pt:
  Solubility:Pyridine; Methanol; Ethanol
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Lee JC., et al. Formosanin C-induced apoptosis requires activation of caspase-2 and change of mitochondrial membrane potential. Cancer Sci. 2009 Mar;100(3):503-13.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting