• Product NameFostemsavir
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityBMS-663068 is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection.
• Target NameHIV Protease inhibitor
• CAS No. 864953-29-7
• Calculated MW 583.5
• Formulation C25H26N7O8P
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CC1=NN(C=N1)C2=NC=C(C3=C2N(C=C3C(=O)C(=O)N4CCN(CC4)C(=O)C5=CC=CC=C5)COP(=O)(O)O)OC
  Pathways:Microbiology&virology; Proteases/Proteasome
  Receptor:HIV-1
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 Mm
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Lalezari JP, et al. Safety and efficacy of the HIV-1 attachment inhibitor prodrug BMS-663068 in treatment-experienced individuals: 24 week results of AI438011, a phase 2b, randomised controlled trial. Lancet HIV. 2015 Oct;2(10):e427-37.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting