• Product Nametak-013
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivitySufugolix (TAK-013) is a highly potent and orally available luteinizing hormone-releasing hormone LHRH receptor with an IC50 of 0.1 nM.
• Target NameLHRH antagonist
• CAS No. 308831-61-0
• Calculated MW 667.72
• Formulation C36H31F2N5O4S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Endocrine system
  SMILES:CN(CC1=CC=CC=C1)CC2=C(SC3=C2C(=O)N(C(=O)N3CC4=C(C=CC=C4F)F)C5=CC=CC=C5)C6=CC=C(C=C6)NC(=O)NOC
  Pathways:Endocrinology/Hormones
  Receptor:human LHRH; monkey LHRH
  Boling pt:
  Melting pt:
  Solubility:DMSO:10 mM/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Sasaki S,et al. Discovery of a thieno[2,3-d]pyrimidine-2,4-dione bearing a p-methoxyureidophenyl moiety at the 6-position: a highly potent and orally bioavailable non-peptide antagonist for the human luteinizing hormone-releasing hormone receptor. J Med Chem. 2003 Jan 2;46(1):113-24.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting