• Product NameNS 638
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityNS-638 is a small nonpeptide molecule with Ca2+-channel blocking properties. K+-stimulated intracellular Ca2+-elevation is blocked with an IC50 value of 3.4 μM.
• Target NameCalcium Channel inhibitor
• CAS No. 150493-34-8
• Calculated MW 325.719
• Formulation C15H11ClF3N3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:C1=CC(=CC=C1CN2C3=C(C=C(C=C3)C(F)(F)F)N=C2N)Cl
  Pathways:Membrane transporter/Ion channel
  Receptor:K+-stimulated intracellular Ca2+-elevation
  Boling pt:
  Melting pt:
  Solubility:DMSO: 34 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. M?ller A,et al. Pharmacological profile and anti-ischemic properties of the Ca(2+)-channel blocker NS-638. Neurol Res. 1995 Oct;17(5):353-60.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting