• Product NameY16
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityY16 is an inhibitor of G-proteinCcoupled Rho GEFs; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated signaling functions.
• Target NameRho inhibitor
• CAS No. 429653-73-6
• Calculated MW 384.43
• Formulation C24H20N2O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CC1=CC(=CC=C1)COC2=CC=CC(=C2)/C=C/3\C(=O)NN(C3=O)C4=CC=CC=C4
  Pathways:Cell Cycle/Checkpoint
  Receptor:Rho GEFs
  Boling pt:
  Melting pt:
  Solubility:DMSO:10 mM
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Yoneda T,et al. The antiproliferative effects of tyrosine kinase inhibitors tyrphostins on a human squamous cell carcinoma in vitro and in nude mice. Cancer Res. 1991 Aug 15;51(16):4430-5.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting