• Product NameCPI-1189
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityREN-1189 is a TNF-a release inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.
• Target NameTNF inhibitor
• CAS No. 183619-38-7
• Calculated MW 234.299
• Formulation C13H18N2O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system/ Immunology system
  SMILES:CC(=O)NC1=CC=C(C=C1)C(=O)NC(C)(C)C
  Pathways:Apoptosis
  Receptor:TNF-α
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Bjugstad KB,et al. Preventive actions of a synthetic antioxidant in a novel animal model of AIDS dementia. Brain Res. 1998 Jun 8;795(1-2):349-57.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting