• Product NameKDM5-inhibitor
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityKDM5 inhibitor
• Target NameHistone Demethylase inhibitor
• CAS No. NA-1
• Calculated MW 278.31
• Formulation C16H14N4O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CCCC1=C(N=C2C(=CNN2C1=O)C#N)C3=CC=CC=C3
  Pathways:Chromatin/Epigenetic
  Receptor:KDM5
  Boling pt:
  Melting pt:
  Solubility:Soluble?in DMSO
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Vinogradova M., et al. An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells. Nat Chem Biol. 2016 Jul;12(7):531-8.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting