• Product NameBTZ043
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityBTZ043 is a inhibitor of decaprenyl-phosphoribose-epimerase (DprE1), It can display nanomolar bactericidal activity against Mycobacterium tuberculosis in vitro.[
• Target NameDprE1 inhibitor
• CAS No. 1161233-85-7
• Calculated MW 431.39
• Formulation C17H16F3N3O5S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Respiratory system/ Immunology system
  SMILES:C[C@H]1COC2(O1)CCN(CC2)C3=NC(=O)C4=CC(=CC(=C4S3)[N+](=O)[O-])C(F)(F)F
  Pathways:Others
  Receptor:DprE1
  Boling pt:
  Melting pt:
  Solubility:DMSO: 13.3 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Norma Alejandra Gonzlez-Martnez et al. In Vivo Activity of the Benzothiazinones PBTZ169 and BTZ043 against Nocardia brasiliensis. PLoS Negl Trop Dis, 2015 Oct, 9(10): e0004022.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting